Oh not sure what class you played and who you had with you but I was infiltrator with biotic bomb from dlc, ran with prothean and liara.
So using wheel to make sure powers hit aiming at exact targets to proc/detonate on. I'd have javik toss his dot persistent proc left liara's singularity right, cloak then use my biotic bomb that I built to have like 40m radius (low dmg but boosted by cloak) to detonate 2 biotic explosions both javik and liara's. Because i fired from cloak the long cool down is mitigated and I only have cloaks short cool down. But for 2 sec after decloak you get the dmg buff here's where you use that wheel to slow time! Follow up the combo with a sniper shot and get that bonus fit that cloak cycle in as well!
The beautiful part is right now while you're reloading that rifle javik and liara's powers just came off cool down so your ready to repeat.
Likewise you can do that with tech chars and even mix the two, Garrus for example has overload and warp. Both powers will both proc and detonate both tech and biotic so if you want half as many biotic booms you can replace them with half as many tech bursts cryo explosions or fire explosions (depending on the kits even all of them - easier to do in the multiplayer).
Speaking of multiplayer this was my game. Had a maxed manifest and could/have solod platinum with half a doz characters.
If you need help im happy too